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1. Yes it is possible to switch between BLE and WiFi operations for CYW4343W. Please check /43xxx_Wi-Fi/doc/WICED-BLE-WiFi-Introducer.pdf, it will be helpful.
Also, there would be overlapping of the spectrums for the radio and you have to enable coexistence to avoid interference. Note that default implementation for the CYW4343W chip is TDM type coexistence. Please check: Overview of SECI
2. You can see Section 18. System Power Consumption in CYW4343W datasheet: https://www.cypress.com/file/298081/download