It is a "Note" and not a warning/error. You should be able to continue with your application if the functionality is unaffected. I tried similar setup at my end and could not recreate the issue. Could you try closing the project and re-opening it. Try a clean and build after that.
At the end, if your load is significant, it is better to buffer the output.
Tried the usual clean-ups that you suggested. However, this popped up on a side project I was using to test the full placement of all components that would be used in the final code. When I went back to the prototype project I was working on using a CYBLE-416045 evaluation board the problem did not appear. I then wiped out the placement test project and started over from scratch. Again, the problem did not pop up.
So for now at least, I am a happy camper. :-)