Hello Sree Hari,
Can you please check if you have assigned the interrupt to correct core. In case you have written the code for CM4 you need to enable the CM4 (Arm CM4 Enable) under the interrupts tab of the design wide resources. Similarly, if you have written the code for CM0+ the you need to enable interrupt for CM0+ core (Arm CM0+ Enable) in the interrupts tab of DWR.
In case this does not solve the problem can you please attach your project here.