Since the CapSense traces are routed on the layer opposite to that of the sensor, it will not cause any crosstalk with other traces running orthogonal.
Even in case of CSX, the Tx and Rx traces are orthogonal and will not cause any crosstalk. The general layout guidelines can be followed as given in CapSense Design Guide, page 115. Link: https://www.cypress.com/file/46081/download
If two traces are running parallel, it is recommended to separate them with a ground trace.
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