You will need to use any Cypress USB-I2C bridge to connect to the bridge control panel. For example if you are using miniprog3 then you will need to connect the SCL,SDA and Ground pins of miniprog3 to the 050 kit. Now in Bridge Control Panel you need to configure the protocol as I2C. Please check Bridge Control Panel help section for configuration on I2C.
After that you can send commands to send/receive I2C data.