We recommend users to go for page programming so that they can get better performance . If single byte programming is needed in your application then you can very well program single byte, there will not be any issues.
There is a maximum of 4 program operations per page, as indicated in table 5.9 on page 37 of the data sheet: http://www.cypress.com/file/207521/download
But it is better to only program once per page. Each page can be partially programmed up to four times.
Hello dear Krishna
I got it .
thanks a lot