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Yes, it is recommended to call blecm_getAvailableTxBuffers() to check if there are buffers are available to send the indication.
This API checks if the controller has free transmit buffers. The controller does not differentiate between notifications, indications or any other L2CAP, SMP or GATT traffic because all this is user data (from above HCI). So you may have unacknowledged packets from previous transfers in the controllers' transmit queue.