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USB-Serial: Can You Change the UART Pin Type? – KBA89356
Question: Is it possible to change the UART pin type (2-pin, 4-pin, or 6-pin) using UART APIs after the device has been programmed?
No. The UART pin type (2-pin, 4-pin, or 6-pin) cannot be changed after the device has been programmed. The UART APIs will allow you to change only the following configurations: 1. Baud rate 2. Data width 3. Stop bits 4. Parity 5. Drop packets on RX error