Kindly check USB-Serial Bridge Controller FAQs – KBA224054(JA) for understanding these queries.
A1. I am not clear what is the expectation for the customer. .cyusb file format can use for configuring these USB-Serial products.
A2. A customer should do it or ask it to programming manufacturer.
Altough it depends on the amount of mass-production, typically, our answer is No. For more detail, contact Cypress FAE or Sales.