You may change all the parameters for the ADC with the helpl vof the APIs. The 4 different possible configurations are built-in into the component and not changeable by you. I would suggest you to check whether the APIs will cover your different settings.
It won't be that simple to change the customizers of the component. Instead, compile the project with one required configuration, copy the macros corresponding to this particular configuration from the header file and then use them in your main.c file or just add them in the original header file corresponding to 4 configs (you shouldn't generate the code as it will go away. so keep a copy of those macros at separate location) and while switching to the new configuration, do whatever component API is doing for other configs manually which would be relatively simple.
