No, the ISR 4.0.1 programming software does not have the Driver support for the windows XP 64 bit. The Operating Systems supported are Windows 98 / Windows 98 Second Edition, Windows ME, Windows NT 4.0.1 Service Pack 5, Windows 2000 Service Pack 1 or later and Windows XP (32 bit). Further, due to resource / expertise constraints, we currently do not have plans to include the driver support for 64 bit platform. Also, our CPLD's are not recommended for new design. The driver for Windows XP operating system is located in C:\Windows\system32\drivers\ezusb.sys. Please try to bind the driver manually and check if the USBISR cable is detected.
Please be noted our entire Cypress CPLD product are Obsolete and not recommended for new design and development. For more information on CPLD product, please visit our webpage: http://www.cypress.com/go/cpld